CNS NOTES

“HIV ENCEPHALITIS “

“ Causes atrophy of the white matter, especially the centrum semiovale.  In adults, it causes the ‘AIDS dementia complex’; in children, it causes HIV-associated progressive encephalopathy.  Appearances improve with treatment. MRI  •  Diffuse bilateral symmetrical periventricular white matter lesions with characteristic sparing of the grey matter•  No enhancement post-contrast•  Cerebral atrophy Axial T2  (a) and …

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Thyroid Cancer

“ US •  Non-specific features NUCLEAR MEDICINE •  Typically, a cold nodule on radio-iodide scan, may be warm/hot on pertechnetate scan.•  Radioactive iodine can be used for detecting metastases—however, this is no good for anaplastic or medullary types. CT •  Bone metastases are typically lytic. ” For Radiology Cases, Discussion join: Radiology Made Easy on …

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TERMINOLOGY FOR DESCRIBING THE LOCATION OF DEGENERATIVE DISC PATHOLOGY

“ Central Overlying the posterior longitudinal ligament. Protrusion tends to be either side of this. Central protrusions are more common in the cervical spine, especially at C6-7 and C5-6. Paracentral/lateral recess This is the most common site for disc protrusion. Foraminal Disc material is present in the intervertebral foramen with inevitable compromise of the exiting …

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“CANAVAN DISEASE”

“ From build-up of N-acetylaspartate (NAA) from enzyme deficiency.  Begins in first year of life.  Macrocephaly and brain enlargement. MRI •  Involvement of all white matter and deep grey matter (especially the basal ganglia and thalami) •  involving the subcortical U-fibers •  Marked NAA peak on MRI spectroscopy ” For Radiology Cases, Discussion join: Radiology Made Easy …

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“ALEXANDER DISEASE”

“ Presents in infancy. Histology shows increased density of Rosenthal fibres. MRI •  Progressive demyelination beginning with the frontal lobes and eventually involving the entire hemispheres •  Enhancement following contrast administration is seen in Alexander’s disease•  Brain enlargement,macrocephaly  ” For Radiology Cases, Discussion join: Radiology Made Easy on Facebook  Subscribe to our youtube channel for …

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